Fmoc-NH-PEG8-CH2CH2COOH Chemical Properties

Boiling point:

781.1±60.0 °C(Predicted)

Density 

1.190±0.06 g/cm3 (20 ºC 760 Torr)

storage temp. 

Sealed in dry,Store in freezer, under -20°C

form 

liquid

pka

4.28±0.10(Predicted)

color 

Colorless to light yellow

InChIKey

VYXGUCLTEWCVRY-UHFFFAOYSA-N

SMILES

C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O

Safety Information

HS Code 

2924297099

Fmoc-NH-PEG8-CH2CH2COOH Usage And Synthesis

Description

Fmoc-N-amido-PEG8-acid is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

Fmoc-NH-PEG8-CH2CH2COOH is used in synthesis of protein-antiviral compound conjugates.

reaction suitability

reaction type: Pegylations

IC 50

Cleavable Linker; PEGs

Fmoc-NH-PEG8-CH2CH2COOH(756526-02-0)Related Product Information

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