Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  Biochemical Engineering >  Inhibitors >  Neuronal Signaling >  BACE inhibitors >  LY2811376

LY2811376

Basic information Safety Supplier Related

LY2811376 Basic information

Product Name:
LY2811376
Synonyms:
  • LY2811376
  • (4S)-4-[2,4-Difluoro-5-(5-pyrimidinyl)phenyl]-5,6-dihydro-4-methyl-4H-1,3-thiazin-2-amine
  • LY 2811376,(4S)-4-[2,4-Difluoro-5-(5-pyriMidinyl)phenyl]-5,6-dihydro-4-Methyl-4H-1,3-thiazin-2-aMine
  • CS-1893
  • LY 2811376;LY-2811376
  • (S)-4-(2,4-difluoro-5-(pyriMidin-5-yl)phenyl)-4-Methyl-5,6-dihydro-4H-1,3-thiazin-2-aMine
  • (4S)-4-(2,4-difluoro-5-pyriMidin-5-ylphenyl)-4-Methyl-5,6-dihydro-1,3-thiazin-2-aMine
  • N-Hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide hydrochloride Tubastatin A HCl LY2811376
CAS:
1194044-20-6
MF:
C15H14F2N4S
MW:
320.36
Product Categories:
  • Inhibitor
  • Inhibitors
Mol File:
1194044-20-6.mol
More
Less

LY2811376 Chemical Properties

Boiling point:
486.5±55.0 °C(Predicted)
Density 
1.42
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
crystalline solid
pka
5.60±0.40(Predicted)
color 
White to khaki
More
Less

LY2811376 Usage And Synthesis

Uses

LY 281137 is a compound capable of the decrease in β-amyloid peptide (Aβ) associated with the cleavage of amyloid precursor protein (APP) by β-secretase (BACE) and γ-secretase. This decrease is important as its hypothesized that the build up of (Aβ) in the brain is a primary cause of neurodegeneration and Alzheimer’s progression.

LY2811376Supplier

Shanghai Tube Pharmaceutical Co., Ltd. Gold
Tel
021-54338626 18017892860
Email
sales@tubepharm.com
Shanghai Boyle Chemical Co., Ltd.
Tel
Email
sales@boylechem.com
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Email
sales@BioChemBest.com
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Jinan Trio PharmaTech Co., Ltd.
Tel
+86 (531) 88811783
Email
sales@trio-pharmatech.com (International market)