tert-Butyl (S)-(5-benzyl-5-azaspiro[2.4]heptan-7-yl)carbamate Chemical Properties

Boiling point:

420.5±34.0 °C(Predicted)

Density 

1.12

storage temp. 

2-8°C

pka

12.31±0.20(Predicted)

InChI

InChI=1S/C18H26N2O2/c1-17(2,3)22-16(21)19-15-12-20(13-18(15)9-10-18)11-14-7-5-4-6-8-14/h4-8,15H,9-13H2,1-3H3,(H,19,21)/t15-/m1/s1

InChIKey

UCBLMUMETZZNIZ-OAHLLOKOSA-N

SMILES

C(OC(C)(C)C)(=O)N[C@H]1C2(CC2)CN(CC2=CC=CC=C2)C1

tert-Butyl (S)-(5-benzyl-5-azaspiro[2.4]heptan-7-yl)carbamate Usage And Synthesis

Synthesis

3.75 g of 5-benzyl-5-azaspiro[2.4]heptan-7-amine was added to the reaction flask, followed by 35 mL of ethanol, 3.75 g of triethylamine and 6.5 g of Boc2O.Stir the reaction at room temperature for 12-14 hours, concentrate, add ethyl acetate, and then use aqueous lemon solution, sodium bicarbonate solution, and saturatedWashed with brine, dried, concentrated and dried to give tert-Butyl (S)-(5-benzyl-5-azaspiro[2.4]heptan-7-yl)carbamate.The yield was 98.2%.

tert-Butyl (S)-(5-benzyl-5-azaspiro[2.4]heptan-7-yl)carbamate(144282-37-1)Related Product Information

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