SACLOFEN Chemical Properties

Melting point:

310-315℃ (decomposition)

Density 

1.437±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

solubility 

0.1 M NaOH: 20 mg/mL

form 

solid

pka

1.15±0.50(Predicted)

color 

white

Water Solubility 

Soluble in water (10mM)

InChIKey

JYLNVJYYQQXNEK-UHFFFAOYSA-N

CAS DataBase Reference

125464-42-8(CAS DataBase Reference)

Safety Information

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

SACLOFEN Usage And Synthesis

Uses

Saclofen is a GABABR antagonist that has been shown to reduced leukocyte migration and increase Fos expression in T7-T11 sympathetic preganglionic neurons

Uses

Saclofen has been used as a GABA_B receptor antagonist to study the analgesic effect of repeated injections of oxycodone in rats.

Definition

ChEBI: 3-amino-2-(4-chlorophenyl)-1-propanesulfonic acid is an organochlorine compound.

Biological Activity

Selective antagonist at GABA B receptors.

Biochem/physiol Actions

Saclofen might possess sympathetic nervous system-dependent anti-inflammatory action.

storage

Room temperature

SACLOFEN(125464-42-8)Related Product Information

• (R)-Saclofen
• SACLOFEN HYDROCHLORIDE
• SACLOFEN((RS)-3-AMINO-2-(4-CHLOROPHENY
• SACLOFEN
• 2-HYDROXYSACLOFEN