Descarboxyl Levofloxacin Chemical Properties

Melting point:

154-158°C

Boiling point:

501.1±50.0 °C(Predicted)

Density 

1.35±0.1 g/cm3(Predicted)

storage temp. 

Refrigerator

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Solid

pka

7.37±0.42(Predicted)

color 

Off-White to Light Yellow

InChI

InChI=1S/C17H20FN3O2/c1-11-10-23-17-15-12(14(22)3-4-21(11)15)9-13(18)16(17)20-7-5-19(2)6-8-20/h3-4,9,11H,5-8,10H2,1-2H3/t11-/m0/s1

InChIKey

XTLCAWXSWVQNHK-NSHDSACASA-N

SMILES

O1C2=C(N3CCN(C)CC3)C(F)=CC3C(=O)C=CN(C2=3)[C@@H](C)C1

CAS DataBase Reference

178964-53-9

Descarboxyl Levofloxacin Usage And Synthesis

Chemical Properties

Off-White to Pale Yellow Solid

Uses

A degradation product of Levofloxacin (L360000).

Descarboxyl Levofloxacin(178964-53-9)Related Product Information

• D-OFLOXACIN
• Levofloxacin N-oxide
• (3S)-10-(4-Ethyl-1-piperazinyl)-9-fluoro-2,3-dihydro-3-Methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid (Levofloxacin IMpurity)
• 2,3,4,5-Tetrafluorobenzoyl chloride
• 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 10-amino-9-fluoro-2,3-dihydro-3-methyl-7-oxo-, (S)- (9CI)
• Levofloxacin Impurity 11
• Levofloxacin Acyl-β-D-glucuronide
• Levofloxacin Impurity 12
• Levofloxacin Impurity 16
• Levofloxacin Impurity 21
• Levofloxacin Impurity 19
• ethyl (S)-10-fluoro-3-methyl-7-oxo- 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate
• Levofloxacin Tetrafluoro Impurity 2
• (3S)-10-Fluoro-2,3-dihydro-3-Methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid
• (3S)-9,10-difluoro-3-methyl-7-oxo-2,3,6,7-tetrahydro-5H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
• Levofloxacin Related Compound C (25 mg) ((S)-ethyl 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylate)
• N,N'-Desethylene Levofloxacin Hydrochloride
• Ethyl (S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylate