28-epirapamycin Chemical Properties

Melting point:

>120°C (dec.)

storage temp. 

-20°C Freezer

solubility 

Dichloromethane (Slightly), DMSO (Slightly), Methanol (Slightly)

form 

Solid

color 

White to Light Yellow

28-epirapamycin Usage And Synthesis

Uses

28-Epirapamycin is an epimer of Rapamycin (R124000), a triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, Rapa’Nui. Used as an immunosuppressant; antirestenotic. Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants.

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