3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester
3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester Basic information
- Product Name:
- 3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester
- Synonyms:
-
- GSK-0660, >=98%
- 3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester
- GSK 0660
- Methyl 3-(N-(2-Methoxy-4-(phenylaMino)phenyl)sulfaMoyl)thiophene-2-carboxylate
- 2-Thiophenecarboxylic acid, 3-[[[2-methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-, methyl ester
- 4-Chloro-3-iodo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine
- METHYL 3-[(4-ANILINO-2-METHOXYPHENYL)SULFAMOYL]THIOPHENE-2-CARBOXYLATE
- 3-(2-Methoxy-4-phenylamino-phenylsulfamoyl)-thiophene-2-carboxylic acid methyl ester
- CAS:
- 1014691-61-2
- MF:
- C19H18N2O5S2
- MW:
- 418.49
- Product Categories:
-
- Inhibitors
- Mol File:
- 1014691-61-2.mol
More
Less
3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester Chemical Properties
- Boiling point:
- 608.1±65.0 °C(Predicted)
- Density
- 1.413±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: soluble10mg/mL, clear
- form
- powder
- pka
- 8.51±0.50(Predicted)
- color
- white to beige
- InChIKey
- NDFKBGWLUHKMFY-UHFFFAOYSA-N
More
Less
3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester Usage And Synthesis
Uses
GSK0660 has been used to study the effects of bezafibrate (BZA) on hypertrophy.
Definition
ChEBI: 3-[(4-anilino-2-methoxyphenyl)sulfamoyl]-2-thiophenecarboxylic acid methyl ester is a sulfonamide.
General Description
GSK0660 has antiangiogenic property in oxygen-induced retinopathy. It also regulates tumor necrosis factor-α (TNFα)-induced inflammation in human retinal microvascular endothelial cells (HRMECs).
Biochem/physiol Actions
GSK0660 is a potent PPARβ/δ antagonist with a pIC50 of 6.8 (160 nM). GSK0660 is nearly inactive on PPARα and PPARγ with IC50s greater than 10 μM.
storage
Store at +4°C
3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylesterSupplier
Shanghai Yunpun industrial Co.,Ltd Gold
- Tel
- 21-61726900 15202122459
- sales@yunpun.com
Shanghai Boyle Chemical Co., Ltd.
- Tel
- sales@boylechem.com
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
Adamas Reagent, Ltd.
- Tel
- 400-6009262 16621234537
- zhangsn@titansci.com
VDM Biochemicals
- Tel
- 0330-2528181
- sales@vdmbio.com