22-Hydroxy-3-oxo-12-ursen-30-oic acid Chemical Properties

Boiling point:

586.0±50.0 °C(Predicted)

Density 

1.14±0.1 g/cm3(Predicted)

pka

4.69±0.70(Predicted)

22-Hydroxy-3-oxo-12-ursen-30-oic acid Usage And Synthesis

Uses

Demethylregelin (Regelin acid), a triterpene, effectively reduces the expression of iNOS protein and subsequent nitric oxide production induced by lipopolysaccharide (HY-D1056) in RAW264.7 cells. Demethylregelin has anti-inflammatory activities[1].

References

[1] Eun Ju Jeong, et al. Anti-inflammatory Triterpenes from Euonymus alatus Leaves and Twigs on Lipopolysaccharide-activated RAW264.7 Macrophage Cells. Bull. Korean Chem. Soc. 2014, Vol. 35, No. 10 2945
[2] Eun Ju Jeong, et al. ChemInform Abstract: Antiinflammatory Triterpenes from Euonymus alatus Leaves and Twigs on Lipopolysaccharide-Activated RAW264.7 Macrophage Cells. March 2015ChemInform 46.

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