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Isoastilbin

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Isoastilbin Basic information

Product Name:
Isoastilbin
Synonyms:
  • Isoastilbin
  • 4H-1-Benzopyran-4-one,3-[(6-deoxy-R-Lmannopyranosyl) oxy]-2-(3,4-dihydroxyphenyl)- 2,3-dihydro-5,7-dihydroxy-,(2R,3S)-
  • 4H-1-Benzopyran-4-one, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-, (2R,3S)-
  • CID 9981176
CAS:
54081-48-0
MF:
C21H22O11
MW:
450.39
Mol File:
54081-48-0.mol
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Isoastilbin Chemical Properties

Melting point:
278-280 °C (decomp)
Boiling point:
801.1±65.0 °C(Predicted)
Density 
1.74±0.1 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
form 
Solid
pka
7.34±0.60(Predicted)
color 
White to off-white
CAS DataBase Reference
54081-48-0
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Isoastilbin Usage And Synthesis

Description

Isoastilbin (IA) is a dihydroflavonol glycoside compound, and studies have shown that IA has a good effect on antioxidants.

Biological Activity

Isoastilbin, a dihydroflavonol glycoside compound in Rhizoma Smilacis glabrae and Astragalus membranaceus. It inhibits glucosyltransferase (GTase) with IC50 value of 54.3 μg/mL, and also inhibits tyrosinase activity. It has neuroprotective, antioxidant, antimicrobial and anti-apoptotic properties and can be used in Alzheimer's disease research.

target

IC50: 54.3 μg/mL (Glucosyltransferase (GTase)

IsoastilbinSupplier

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