(R)-TERT-LEUCINOL Chemical Properties

Melting point:

30-33 °C(lit.)

Boiling point:

70 °C0.4 mm Hg(lit.)

Density 

0.9 g/mL at 25 °C(lit.)

Flash point:

194 °F

storage temp. 

Keep in dark place,Inert atmosphere,2-8°C

form 

Liquid

pka

12.88±0.10(Predicted)

color 

Colorless to yellow

optical activity

[α]20/D 37°, c = 1.5 in ethanol

InChI

InChI=1S/C6H15NO/c1-6(2,3)5(7)4-8/h5,8H,4,7H2,1-3H3/t5-/m0/s1

InChIKey

JBULSURVMXPBNA-YFKPBYRVSA-N

SMILES

C(O)[C@H](N)C(C)(C)C

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HS Code 

2922190090

(R)-TERT-LEUCINOL Usage And Synthesis

Uses

(R)-Tert-leucinol (H-D-Tle-ol) is a chiral molecular compound with optical activity and its enantiomeric form is (S)-tert-leucinol. (R)-Tert-leucinol belongs to the class of α-amino alcohols, which have certain biological activities and are potent reversible inhibitors of protein synthesis. (R)-Tert-leucinol can be used as a chiral ligand for asymmetric catalytic reactions. Its derivatives are also used as optical splitting reagents, for peptidyl alcohol synthesis in peptide drugs, and as inhibitors of protein hydrolysis.

reaction suitability

reaction type: solution phase peptide synthesis

(R)-TERT-LEUCINOL(112245-09-7)Related Product Information

• Fmoc-L-tert-leucine
• Vincristine sulfate
• L-tert-Leucine
• FMOC-D-ALPHA-T-BUTYLGLYCINE
• METHYLLYCACONITINE CITRATE
• BOC-D-ALPHA-T-BUTYLGLYCINE
• L-tert-Leucine methyl ester hydrochloride
• D-tert-Butylglycine
• DELCORINE
• (S)-(-)-4-TERT-BUTYL-2-OXAZOLIDINONE
• (R)-(+)-4-TERT-BUTYL-2-OXAZOLIDINONE
• (-)-CHIRACAMPHOX
• Valrubicin
• (R)-TERT-LEUCINOL
• Cbz-L-tert-Leucine
• (S,S)-2,2'-METHYLENEBIS(4-TERT-BUTYL-2-OXAZOLINE)
• (S,S)-(-)-2,2'-ISOPROPYLIDENEBIS(4-TERT-BUTYL-2-OXAZOLINE)
• Z-TLE-OH DCHA