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5-Bromo-3-(trifluoromethyl)-2-pyridinecarbonitrile

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5-Bromo-3-(trifluoromethyl)-2-pyridinecarbonitrile Basic information

Product Name:
5-Bromo-3-(trifluoromethyl)-2-pyridinecarbonitrile
Synonyms:
  • 5-Bromo-3-(trifluoromethyl)-2-pyridinecarbonitrile
  • 5-BroMo-3-(trifluoroMethyl)picolinonitrile
  • 5-Bromo-2-cyano-3-(trifluoromethyl)pyridine, 5-Bromo-3-(trifluoromethyl)picolinonitrile
  • 5-Bromo-3-(trifluoromethyl)pyridine-2-carbonitrile
  • 5-Bromo-2-cyano-3-(trifluoromethyl)
  • 2-Pyridinecarbonitrile, 5-bromo-3-(trifluoromethyl)-
  • 5-Bromo-3-(trifluoromethyl)-2-pyridinecarbonitrile ISO 9001:2015 REACH
  • (Trifluoromethyl)-2-Pyridinecarbonitrile
CAS:
1214377-57-7
MF:
C7H2BrF3N2
MW:
251
Product Categories:
  • Fluorine series
Mol File:
1214377-57-7.mol
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5-Bromo-3-(trifluoromethyl)-2-pyridinecarbonitrile Chemical Properties

Boiling point:
257℃
Density 
1.81
Flash point:
110℃
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
-5.10±0.20(Predicted)
color 
White to Off-White
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Safety Information

HS Code 
2933399990
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5-Bromo-3-(trifluoromethyl)-2-pyridinecarbonitrile Usage And Synthesis

Uses

5-bromo-3-(trifluoromethyl)pyridine-2-carbonitrile is used as an apalutamide intermediate. Apalutamide is an FDA-approved second-generation androgen receptor (AR) inhibitor for the treatment of patients with non-metastatic CRPC.

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