15-Azido-4,7,10,13-tetraoxapentadecanoic acid Chemical Properties

storage temp. 

-20°C

solubility 

DMSO : 100 mg/mL (343.29 mM; Need ultrasonic)

form 

Liquid

color 

Colorless to Pale Yellow

Safety Information

HS Code 

29270000

15-Azido-4,7,10,13-tetraoxapentadecanoic acid Usage And Synthesis

Description

Azido-PEG4-acid is a very popular PEG reagent containing an azide group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Chemical Properties

Light yellow to colorless thick liquid

Uses

Azido-PEG4-Acid is amine- or phosphine-reactive building block used to derivative primary amines for ligation to alkyne-tagged molecules.

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