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m-PEG8-NHS ester

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m-PEG8-NHS ester Basic information

Product Name:
m-PEG8-NHS ester
Synonyms:
  • MPEG7-NHS
  • MPEG7-CH2CH2COONHS Ester
  • Methyl-PEG8-NHS Ester
  • 1-[(1-Oxo-4,7,10,13,16,19,22,25-octaoxahexacos-1-yl)oxy]-2,5-pyrrolidinedione
  • 4,7,10,13,16,19,22,25-Octaoxahexacosanoic acid 2,5-dioxo-1-pyrrolidinyl ester
  • Methyl-PEG8-NHS Ester
  • m-PEG8-NHS ester
  • MeO-dPEG(8)-NHS
CAS:
756525-90-3
MF:
C22H39NO12
MW:
509.54
Mol File:
756525-90-3.mol
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m-PEG8-NHS ester Chemical Properties

storage temp. 
-20°C
solubility 
Soluble in DMSO, DCM, DMF
form 
solid or viscous liquid
color 
Colorless to Yellow
InChI
InChI=1S/C22H39NO12/c1-27-6-7-29-10-11-31-14-15-33-18-19-34-17-16-32-13-12-30-9-8-28-5-4-22(26)35-23-20(24)2-3-21(23)25/h2-19H2,1H3
InChIKey
IBZNTYBFTKFSMU-UHFFFAOYSA-N
SMILES
C(ON1C(=O)CCC1=O)(=O)CCOCCOCCOCCOCCOCCOCCOCCOC
CAS DataBase Reference
756525-90-3
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Safety Information

HS Code 
2942000090
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m-PEG8-NHS ester Usage And Synthesis

Description

m-PEG8-NHS ester is a PEG linker containing an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer increases solubility in aqueous media.

in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

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