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O-De(3-fluorobenzyl) Lapatinib

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O-De(3-fluorobenzyl) Lapatinib Basic information

Product Name:
O-De(3-fluorobenzyl) Lapatinib
Synonyms:
  • O-De(3-fluorobenzyl) Lapatinib
  • Lapatinib IMpurity 1
  • 2-chloro-4-((6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-yl)amino)phenol
  • Lapatinib Impurity 1 (O-De(3-fluorobenzyl) Lapatinib)
  • Lapatinib Impurity 20
  • Lapatinib Impurity 1 (O-De(3-fluorobenzyl) Lapatinib) Ditosylate Salt
  • Lapatinib Impurity 35
  • Lapatinib O-Desfluorobenzyl Imp
CAS:
1268997-70-1
MF:
C22H21ClN4O4S
MW:
472.94
Product Categories:
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Aromatics
  • Metabolites & Impurities
  • Pharmaceuticals
  • Sulfur & Selenium Compounds
Mol File:
1268997-70-1.mol
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O-De(3-fluorobenzyl) Lapatinib Chemical Properties

solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
Pale Yellow to Yellow
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O-De(3-fluorobenzyl) Lapatinib Usage And Synthesis

Uses

A reactive metabolite of Lapatinib (L175800) which is associated with various drug toxicities. Lapatinib is metabolized mainly by P450 3A4 to form O- and N-dealkylated metabolites.

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