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Nodinitib-1

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Nodinitib-1 Basic information

Product Name:
Nodinitib-1
Synonyms:
  • Nodinitib-1
  • 1H-BenziMidazol-2-aMine, 1-[(4-Methylphenyl)sulfonyl]-
  • ML 130
  • 1-[(4-Methylphenyl)sulfonyl]-1H-benziMidazol-2-aMine
  • Noditinib-1
  • ML130 (Nodinitib-1)
  • CID-1088438
  • 1-[(4-Methylphenyl)sulfonyl]-1H-benzimidazol-2-ylamine
CAS:
799264-47-4
MF:
C14H13N3O2S
MW:
287.34
Product Categories:
  • API
  • NF-kB
  • Amines
  • Aromatics
  • Heterocycles
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds
Mol File:
799264-47-4.mol
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Nodinitib-1 Chemical Properties

Melting point:
191-192 °C (decomp)
Boiling point:
532.5±43.0 °C(Predicted)
Density 
1.40±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
solubility 
DMSO: >10mg/mL
form 
powder
pka
2.55±0.10(Predicted)
color 
white to beige
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
3
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Nodinitib-1 Usage And Synthesis

Uses

Noditinib-1 is a potent and selective inhibitor of NOD1-induced NF-κB activation. Mutations in NOD proteins have been associated with various inflammatory diseases and Noditinib-1 shows promise as a potential therapeutic agent.

Definition

ChEBI: 1-(4-methylphenyl)sulfonyl-2-benzimidazolamine is a sulfonamide.

Nodinitib-1Supplier

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