Basic information Safety Supplier Related

Dimethyl 2-oxoglutarate

Basic information Safety Supplier Related

Dimethyl 2-oxoglutarate Basic information

Product Name:
Dimethyl 2-oxoglutarate
Synonyms:
  • DIMETHYL 2-OXOGLUTARATE
  • DIMETHYL 2-KETOGLUTARATE
  • DIMETHYL OXOGLUTARATE
  • ALPHA-Ketoglutaric acid dimethyl ester
  • 2-KETOGLUTARIC ACID DIMETHYL ESTER (ALPHA-) 95+%
  • α-Ketoglutaric acid dimethyl ester
  • Dimethyl 2-oxopentanedioate
  • ethyl 2-oxoglutarate
CAS:
13192-04-6
MF:
C7H10O5
MW:
174.15
Product Categories:
  • Amino Acids 13C, 2H, 15N
  • Amino Acids & Derivatives
  • Miscellaneous Reagents
  • C6 to C7
  • Carbonyl Compounds
  • Esters
Mol File:
13192-04-6.mol
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Dimethyl 2-oxoglutarate Chemical Properties

Boiling point:
90-95 °C0.4 mm Hg(lit.)
Density 
1.203 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.439(lit.)
Flash point:
>230 °F
storage temp. 
-20°C
solubility 
DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 10 mg/ml
form 
clear liquid
color 
Colorless to Light yellow to Light orange
CAS DataBase Reference
13192-04-6(CAS DataBase Reference)
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Safety Information

WGK Germany 
3
HS Code 
29183000

MSDS

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Dimethyl 2-oxoglutarate Usage And Synthesis

Chemical Properties

Slight Yellow Liquid

Uses

Dimethyl 2-oxoglutarate may be used to synthesize the conformationally constrained PNA (peptide nucleic acid) -monomer capable of binding thymine in a triplex motif. It may be used in the synthesis of 4-aryl kainic acid analogs, via highly stereoselective Michael addition reaction with nitrostyrene.

Definition

ChEBI: Dimethyl 2-oxoglutarate is an oxo carboxylic acid.

General Description

Dimethyl 2-oxoglutarate is a key intermediate formed during the Krebs cycle and an important nitrogen transporter in the biological metabolic pathways. The electrochemical behavior of dimethyl-2-oxoglutarate has been investigated by cyclic voltammetry, square wave voltammetry and differential pulse voltammetry using a glassy carbon electrode.

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