Valdecoxib IMpurity B Chemical Properties

Melting point:

>271°C (dec.)

Boiling point:

732.7±70.0 °C(Predicted)

Density 

1.343±0.06 g/cm3(Predicted)

storage temp. 

-20°C Freezer

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

-4.23±0.40(Predicted)

form 

Solid

color 

White to Off-White

InChI

InChI=1S/C32H25N3O6S2/c1-21-29(31(33-40-21)25-9-5-3-6-10-25)23-13-17-27(18-14-23)42(36,37)35-43(38,39)28-19-15-24(16-20-28)30-22(2)41-34-32(30)26-11-7-4-8-12-26/h3-20,35H,1-2H3

InChIKey

FDUYPVXQEAKTGG-UHFFFAOYSA-N

SMILES

C1(S(NS(C2=CC=C(C3=C(C)ON=C3C3=CC=CC=C3)C=C2)(=O)=O)(=O)=O)=CC=C(C2=C(C)ON=C2C2=CC=CC=C2)C=C1

Valdecoxib IMpurity B Usage And Synthesis

Uses

Valdecoxib Dimer is a dimeric impurity of the cyclooxygenase-2 inhibitor, Valdecoxib (V090000).

Valdecoxib IMpurity B(1373038-60-8)Related Product Information

• Valdecoxib IMpurity D
• 4-(4-chlorophenyl)-5-methyl-3-phenylisoxazole
• 4-[(5-Methyl-3-phenyl-4-isoxazolyl)methyl]benzenesulfonamide
• 3-methyl -4,5-diphenyl-4,5-didydro-isoxazole
• Valdecoxib 3'-SulfonaMide IMpurity
• Ezetimibe Impurity
• (3R,4R)-3-[(6-amino-4-pyrimidinyl)methylamino]-4-methyl-β-oxo-1-Piperidinepropanenitrile
• 4-[(5-Methyl-3-phenyl-4-isoxazolyl)methyl]benzenesulfonyl chloride
• Parecoxib Impurity H
• Acotiamide Impurity
• Valdecoxib IMpurity-E
• BenzenesulfonaMide, 3-[4-[4-(aMinosulfonyl)phenyl]-5-Methyl-3-isoxazolyl]-
• 5-METHYL-3,4-DIPHENYL-4,5-DIHYDROISOXAZOL-5-OL
• N-((4-(5-Methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)isobutyraMide
• Valdecoxib IMpurity F
• 4-(3-methyl-4-phenylisoxazol-5-yl)benzenesulfonamide
• 4-(5-methyl-4-phenylisoxazol-3-yl)benzenesulfonamide
• N-((4-(5-Methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)acetaMide