Loratadine EP IMpurity F Chemical Properties

Melting point:

149-153 °C

Boiling point:

490.3±45.0 °C(Predicted)

Density 

1.29±0.1 g/cm3(Predicted)

solubility 

Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)

pka

3.65±0.40(Predicted)

Loratadine EP IMpurity F Usage And Synthesis

Uses

Loratadine Impurity F (Loratadine EP Impurity F; Loratadine USP Related Compound G Impurity) is a fluorinated analog of Loratadine (L469575), which is a nonsedating-type histamine H1-receptor.

Loratadine EP IMpurity F(125743-80-8)Related Product Information

• (1-Methyl-4-piperidinyl)[3-[2-(3-chlorophenyl)ethyl]pyridinyl]methanone hydrochloride
• 8-Chloro-6,11-dihydro-11-(1-methyl-4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol
• Sch 37370
• 4,8-Dichloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-β]pyridin-11-one (Loratadine Impurity)
• 3,5-Lutidine
• 4-(8-Chloro-6,11-dihydro-11-hydroxy-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-piperidinecarboxylic Acid Ethyl Ester
• Desloratadine Impurity
• N-Methyl Desloratadine
• 4-chloro-loratadine
• Loratadine EP Impurity E
• Loratadine
• 8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one
• N-Carbethoxy-4-piperidone
• Desloratadine
• 3-Hydroxy loratadine
• Desloratadine N-Hydroxypiperidine
• 8-Dechloro-10-chloro Loratadine
• Loratadine Impurity 17