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2'-O-Methylkurarinone

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2'-O-Methylkurarinone Basic information

Product Name:
2'-O-Methylkurarinone
Synonyms:
  • 2'-O-Methylkurarinone
  • Kurarinone, 2'-O-methyl-
  • (2S)-2-Methoxykurarinone
  • 4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxy-2-methoxyphenyl)-5-methoxy-8-[(2R)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]-, (2S)-
  • (2S)-7-hydroxy-2-(4-hydroxy-2-methoxyphenyl)-5-methoxy-8-[(2R)-5-methyl-2-prop-1-en-2-ylhex-4-enyl]-2,3-dihydrochromen-4-one
  • (2S)-2-methoxykurarinoneQ: What is (2S)-2-methoxykurarinone Q: What is the CAS Number of (2S)-2-methoxykurarinone
  • inhibit,Inhibitor,(2S) 2' Methoxykurarinone,(2S)2'Methoxykurarinone
  • 2'-Methoxykurarinone
CAS:
270249-38-2
MF:
C27H32O6
MW:
452.54
Mol File:
270249-38-2.mol
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2'-O-Methylkurarinone Chemical Properties

Melting point:
112-115℃
Boiling point:
643.6±55.0 °C(Predicted)
Density 
1.171±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
pka
7.50±0.40(Predicted)
color 
Light yellow to brown
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2'-O-Methylkurarinone Usage And Synthesis

Uses

2''-Methoxykurarinone can be used to determine the cytotoxic effects of flavonoids from root of Sophora flavescens in cancer cells.

Definition

ChEBI: (2S)-2'-methoxykurarinone is a dimethoxyflavanone that is (2S)-(-)-kurarinone in which the hydroxy group at position 2' is replaced by a methoxy group. Isolated from the roots of Sophora flavescens, it exhibits cytotoxicity against human myeloid leukemia HL-60 cells. It has a role as a metabolite and an antineoplastic agent. It is a dimethoxyflavanone, a dihydroxyflavanone and a member of 4'-hydroxyflavanones. It is functionally related to a (2S)-(-)-kurarinone.

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