N-Acetyl Retigabine Chemical Properties

Melting point:

153-155°C

Boiling point:

509.6±50.0 °C(Predicted)

Density 

1.306±0.06 g/cm3(Predicted)

Flash point:

2℃

storage temp. 

-20°C

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

14.38±0.70(Predicted)

color 

Pale Grey to Brown

Safety Information

Hazard Codes 

F,Xn

Risk Statements 

11-20/21/22-36

Safety Statements 

16-36/37

RIDADR 

UN 1648 3 / PGII

WGK Germany 

2

N-Acetyl Retigabine Usage And Synthesis

Uses

N-Acetyl N-Descarboxyethyl Retigabine, is a metabolite of Retigabine (R189050), a new experimental anticonvulsant drug. Anxiolytic.

General Description

A Certified Spiking Solution^? suitable for use in retigabine testing methods by LC/MS or GC/MS for applications in clinical toxicology, medication monitoring, urine drug testing, pharmaceutical research, or forensic analysis. N-Acetylretigabine is the primary urinary metabolite of retigabine, a new antiepileptic drug developed for treatment of partial seizures. Also known as ezogabine, the drug is marketed under the trade names Potiga^? in the US and Trobalt in the EU.

N-Acetyl Retigabine(229970-68-7)Related Product Information

• Ranolazine Bis(N-Oxide)
• NA
• Rasagiline N-Carbamoyl Glucuronide
• 1-Piperazineethanol, a-[(2-methoxyphenoxy)methyl]-
• Desmethyl Ranolazine
• Retigabine 3,3''-Dimer
• 4-(4-Fluorobenzylamino)-1,2-phenylenediamine
• 2-AMino-4-[(4-fluorobenzyl)aMino]-1-nitrobenzene(RETIGABINE inteMediate)
• Retigabine Dihydrochloride
• Retigabine N-β-D-Glucoside
• (4-Amino-2-nitrophenyl)carbamic acid ethyl ester
• 2-Amino-5-[(4-fluorobenzyl)amino]-1-nitrobenzene
• Retigabine-d4 Dihydrochloride
• N-(2-Amino-4-nitrophenyl)carbamic Acid Ethyl Ester
• Acetylcholine