Basic information Uses Safety Supplier Related

Regorafenib iMpurity

Basic information Uses Safety Supplier Related

Regorafenib iMpurity Basic information

Product Name:
Regorafenib iMpurity
Synonyms:
  • Regorafenib Monohydrate Impurity
  • Regorafenib Monohydrate IMP
  • Regorafenib Impurity 30
  • Regorafenib impurity 3/Regorafenib Urea Impurity/1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(2-fluoro-4-hydroxyphenyl)urea
  • Regorafenib Urea Impurity
  • Urea, N-[4-chloro-3-(trifluoromethyl)phenyl]-N'-(2-fluoro-4-hydroxyphenyl)-
  • AFP-CTF urea impurity (Regorafenib impurity)
  • Azilsartan medoxomil impurity260
CAS:
1333390-56-9
MF:
C14H9ClF4N2O2
MW:
348.68
Mol File:
1333390-56-9.mol
More
Less

Regorafenib iMpurity Chemical Properties

Boiling point:
346.9±42.0 °C(Predicted)
Density 
1.599±0.06 g/cm3(Predicted)
pka
9.21±0.31(Predicted)
More
Less

Regorafenib iMpurity Usage And Synthesis

Uses

The impurity 1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(3-fluoro-4-hydroxyphenyl)urea is an impurity with the structure shown below that is generated during the production of regorafenib. Regorafenib is a novel multi-kinase inhibitor developed by Bayer AG. It targets tumorigenesis, tumor angiogenesis, and the maintenance of tumor microenvironment signaling by inhibiting multiple tumor-promoting protein kinases.

Regorafenib iMpuritySupplier

Shenzhen DaerSen Science and Technology Co., Ltd.
Tel
0755-84551027
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Email
sales@chem-strong.com
Pharmacodia (Beijing) Co.,Ltd
Tel
+86-400-851-9921
Email
sales@pharmacodia.com
Shanghai SuperLan Chemcial Technique Centre
Tel
0-2022843681 15618226720
Email
chaolaichem@foxmail.com
Shanghai Rlavie Technology Co., Ltd.
Tel
21-67759270 17717059219
Email
sales@rlavie.com
More
Less

Regorafenib iMpurity(1333390-56-9)Related Product Information