4-Methylumbelliferyl beta-D-galactoside
4-Methylumbelliferyl beta-D-galactoside Basic information
- Product Name:
- 4-Methylumbelliferyl beta-D-galactoside
- Synonyms:
-
- MUG
- MU-GAL
- MUGALACTOSIDE
- MUGGAL
- 4-METHYLUMBELLIFERYL-b-D- GALACTOPYRANOSIDE extrapure
- 4-methylumberiferryl-beta-D-galactopyranoside
- MUG, MUGA
- 4-Methyl-7-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one
- CAS:
- 6160-78-7
- MF:
- C16H18O8
- MW:
- 338.31
- EINECS:
- 228-185-5
- Product Categories:
-
- substrate
- Substrates
- Enzyme Substrates
- Fluorescent Labels & Indicators
- Labeling and Diagnostics Reagents
- Mol File:
- 6160-78-7.mol
4-Methylumbelliferyl beta-D-galactoside Chemical Properties
- Melting point:
- 258-263 °C (dec.)
- alpha
- -64 º (c=1, pyridine, after)
- Boiling point:
- 626.9±55.0 °C(Predicted)
- Density
- 1.522±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- Soluble in DMSO (40 mg/ml)
- pka
- 12.73±0.70(Predicted)
- form
- Powder
- color
- White to slightly off-white
- Water Solubility
- soluble
- Sensitive
- Moisture Sensitive & Hygroscopic
- BRN
- 94673
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
- CAS DataBase Reference
- 6160-78-7(CAS DataBase Reference)
MSDS
- Language:English Provider:7-(beta-D-Galactopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
- Language:English Provider:ALFA
4-Methylumbelliferyl beta-D-galactoside Usage And Synthesis
Description
4-MUG (6160-78-7) is a versatile fluorogenic substrate for ?-galactosidase1 for use in cell extracts or purified enzyme preparations.1-3? This substrate produces a water soluble blue fluorescent coumarin fluorophore. Ex: 342 nm; Em: 441 nm
Chemical Properties
White Powder
Uses
Substrate for fluorometric assay of ?-D-galactosidase
Uses
It is a substrate used for fluorometric assay for β-galactosidase. It is used to detect E-coli n the fluorogenic medium.
Definition
ChEBI: A beta-D-galactoside having a 4-methylumbelliferyl substituent at the anomeric position.
References
Chiu et al. (2017), Measuring ?-Galactosidase Activity in Gram-Positive Bacteria Using a Whole-Cell Assay with MUG as a Fluorescent Reporter; Curr. Protoc. Toxicol., Supp 74 4.44.1 Kytidou et al. (2018), Nicotiana benthamiana α-galactosidase A1,1 can functionally complement human α-galactosidase A deficiency associated with Fabry disease; J. Biol. Chem., 293 10042 Hernandez-Guzman et al. (2016), Purification and characterization of an extracellular ?-glucosidase from Sporothrix schenckii; FEBS Open Bio., 6 1067
4-Methylumbelliferyl beta-D-galactosideSupplier
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4-Methylumbelliferyl beta-D-galactoside(6160-78-7)Related Product Information
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