Basic information Safety Supplier Related

8-EpitacroliMus

Basic information Safety Supplier Related

8-EpitacroliMus Basic information

Product Name:
8-EpitacroliMus
Synonyms:
  • 8-EpitacroliMus
  • [3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8R*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]- 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-pro
  • Tacrolimus Impurity 1(Tacrolimus 8-Epimer)
  • Tacrolmius 8-epimer
  • Tacrolimum 8-Epimer
  • Tacrolimus Impurity 1(Tacrolimus EP Impurity D)(Tacrolimus 8-Epimer)
  • Tacrolimus 8-Epimer/8-epi Tacrolimus
  • Tacrolimus EP Impurity D (8-epi Tacrolimus)
CAS:
129212-35-7
MF:
C44H69NO12
MW:
804.02
Product Categories:
  • Chiral Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:
129212-35-7.mol
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8-EpitacroliMus Chemical Properties

Boiling point:
871.7±75.0 °C(Predicted)
Density 
1.19±0.1 g/cm3(Predicted)
solubility 
Chloroform (Slightly), Methanol (Slightly, Heated, Sonicated)
pka
9.97±0.70(Predicted)
form 
Solid
color 
White to Pale Yellow
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Safety Information

HS Code 
2934990002
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8-EpitacroliMus Usage And Synthesis

Chemical Properties

Pale Yellow Solid

Uses

8-Epitacrolimus is a new l-pipecolic acid macrolide lactone, an important immunosuppressive drug that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. 8-Epitacrolimus is also an Epimer of Tacrolimus (F370000).

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