Rimantadine hydrochloride Chemical Properties

Melting point:

>300 °C(lit.)

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly), Water(Slightly)

form 

Solid

color 

White to Off-White

Water Solubility 

Freely soluble in water.

Merck 

14,8224

InChI

InChI=1S/C12H21N.ClH/c1-8(13)12-5-9-2-10(6-12)4-11(3-9)7-12;/h8-11H,2-7,13H2,1H3;1H

InChIKey

OZBDFBJXRJWNAV-UHFFFAOYSA-N

SMILES

C1C2CC3(C(N)C)CC1CC(C3)C2.Cl

CAS DataBase Reference

1501-84-4

Safety Information

Hazard Codes 

Xn

Risk Statements 

22-36/37/38

Safety Statements 

26-36

WGK Germany 

3

RTECS 

AU4717000

HS Code 

29213000

Toxicity

LD50 oral in rat: 640mg/kg

MSDS

• Language:English Provider:SigmaAldrich

Rimantadine hydrochloride Usage And Synthesis

Description

Rimantadine hydrochloride is an antiviral analogue of amantadine, reportedly useful in the prophylaxis and treatment of influenza A. Compared with amantadine, nmantadine appears to have a lower side-effect profile.

Chemical Properties

White Crystalline Solid

Originator

DuPont (USA)

Uses

Rimantadine Hydrochloride is used as an antiviral agent.

Definition

ChEBI: Rimantadine hydrochloride is an organic molecular entity.

brand name

Flumadine (Forest);Roflual.

References

[1] koff w c, elm jr j l, halstead s b. suppression of dengue virus replication in vitro by rimantadine hydrochloride[j]. the american journal of tropical medicine and hygiene, 1981, 30(1): 184-189.
[2] koff w c, peavy d l, knight v. inhibition of in vitro proliferative responses of human lymphocytes by rimantadine hydrochloride[j]. infection and immunity, 1979, 23(3): 665-669.
[3] hayden f g, monto a s. oral rimantadine hydrochloride therapy of influenza a virus h3n2 subtype infection in adults[j]. antimicrobial agents and chemotherapy, 1986, 29(2): 339-341.

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