WAY100635 Chemical Properties

storage temp. 

Store at -20°C

solubility 

≥53.9 mg/mL in DMSO; ≥51.2 mg/mL in EtOH; ≥6.08 mg/mL in H2O with ultrasonic

form 

solid

color 

White to off-white

Water Solubility 

Soluble to 25 mM in water

Safety Information

HS Code 

2933.59.8000

WAY100635 Usage And Synthesis

Description

WAY-100635 is a potent, silent antagonist of serotonin 5-HT_1A receptors with an IC₅₀ value of 2.2 nM (K_i = 0.8 nM) for inhibiting 5-HT_1A receptors in rat hippocampal membranes. Because it displays 100-fold selectivity for 5-HT_1A over other 5-HT subtypes, WAY-100635 is classically used to examine the distribution and function of 5-HT_1A receptors. However, WAY-100635 has also been shown to exhibit agonist activity at dopamine D₄ receptors (K_d = 2.4 nM).

storage

Desiccate at RT

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