Basic information Safety Supplier Related

Sofosbuvir IMpurity

Basic information Safety Supplier Related

Sofosbuvir IMpurity Basic information

Product Name:
Sofosbuvir IMpurity
Synonyms:
  • Sofosbuvir IMpurity
  • Sofosbuvir Phosphate Impurity
  • Sofosbuvir Phenoxyphosphinyl Impurity
  • L-Alanine, N-(hydroxyphenoxyphosphinyl)-, 1-methylethyl ester
  • Sofosbuvir Impurity 114
  • SofosbuvirImpurity43CyclohexylamineSalt
  • (2S)-Isopropyl 2-((hydroxy(phenoxy)phosphoryl)amino)propanoate (Sofosbuvir Impurity)
CAS:
1520010-86-9
MF:
C12H18NO5P
MW:
287.25
Mol File:
1520010-86-9.mol
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Sofosbuvir IMpurity Usage And Synthesis

Uses

Isopropyl N-(Hydroxyphenoxyphosphinyl)alaninate Sodium Salt is an impurity of Sofosbuvir (P839640), a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

Sofosbuvir IMpuritySupplier

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