N,N-DIETHYLMETHACRYLAMIDE Chemical Properties

Boiling point:

82-84°C 7mm

Density 

0.901 g/mL at 25 °C

refractive index 

n20/D1.455

Flash point:

83℃

storage temp. 

2-8°C

form 

liquid

Safety Information

RIDADR 

UN 1993 / PGIII

WGK Germany 

3

N,N-DIETHYLMETHACRYLAMIDE Usage And Synthesis

Uses

Since the lower critical solution temperature (LCST) is around body temperature, it is widely used in the development of drug delivery systems based on the sol gel phase conversion at body temperature.

General Description

Post polymerization, N, N-Diethyl methacrylamide gels show temperature sensitivity because of their lower critical solution temperature (LCST). This acrylamide is commonly polymerized to form temperature sensitive hydrogels. The presence of a hydrophobic group (methyl and ethyl group in this case) is characteristic in temperature sensitive polymers. Water solubility in such polymers decreases with increase in temperature.

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