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IVHD-valtrate

Basic information Safety Supplier Related

IVHD-valtrate Basic information

Product Name:
IVHD-valtrate
Synonyms:
  • IVHD-valtrate
  • Isovaleroxyhydroxydidrovaltratum
  • Isovaleroxyhydroxydihydrovaltrate
  • Valtrate HD
  • Butanoic acid, 3-methyl-2-(3-methyl-1-oxobutoxy)-, [(1S,2'R,4aR,6S,7aS)-6-(acetyloxy)-4a,5,6,7a-tetrahydro-4a-hydroxy-1-(3-methyl-1-oxobutoxy)spiro[cyclopenta[c]pyran-7(1H),2'-oxiran]-4-yl]methyl ester
CAS:
28325-56-6
MF:
C27H40O11
MW:
540.6
Mol File:
28325-56-6.mol
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IVHD-valtrate Usage And Synthesis

Biological Activity

IVHD-valtrate is an active Valeriana jatamansi derivative that inhibits human ovarian cancer cells in vitro and in vivo. It induces apoptosis of cancer cells and inhibits ovarian cancer cells from arresting in G2/M phase. It has the potential to be a new chemotherapeutic agent for human ovarian cancer research.

in vitro

IVHD-valtrate inhibits the growth and proliferation of the A2780 and OVCAR-3 ovarian cancer cell lines in a concentration-dependent manner. IVHD-valtrate results in a relatively low cytotoxicity to immortalized non-tumorigenic human ovarian surface epithelial cells (IOSE-144).

target

IC50: apoptosis

IVHD-valtrateSupplier

BioBioPha Co., Ltd.
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Wuxi Zhongkun Biochemical Technology Co., Ltd.
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EMMX Biotechnology LLC
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Shanghai YuanYe Biotechnology Co., Ltd.
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Beijing Jin Ming Biotechnology Co., Ltd.
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010-60605840 18892239720
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