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ChemicalBook >  Product Catalog >  Biochemical Engineering >  Inhibitors >  Mitogen-activated protein kinase (MAPK) >  JNK activator >  (R)-2-((R)-2-acetamido-3-(4-hydroxyphenyl)propanamido)-N-((R)-1-amino-1-oxo-3-phenylpropan-2-yl)-5-guanidinopentanamide

(R)-2-((R)-2-acetamido-3-(4-hydroxyphenyl)propanamido)-N-((R)-1-amino-1-oxo-3-phenylpropan-2-yl)-5-guanidinopentanamide

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(R)-2-((R)-2-acetamido-3-(4-hydroxyphenyl)propanamido)-N-((R)-1-amino-1-oxo-3-phenylpropan-2-yl)-5-guanidinopentanamide Basic information

Product Name:
(R)-2-((R)-2-acetamido-3-(4-hydroxyphenyl)propanamido)-N-((R)-1-amino-1-oxo-3-phenylpropan-2-yl)-5-guanidinopentanamide
Synonyms:
  • DTP3
  • (R)-2-((R)-2-acetamido-3-(4-hydroxyphenyl)propanamido)-N-((R)-1-amino-1-oxo-3-phenylpropan-2-yl)-5-guanidinopentanamide
  • D-Phenylalaninamide, N-acetyl-D-tyrosyl-D-arginyl-
  • (R)-2-((R)-2-acetamido-3-(4-hydroxyphenyl)propanamido)-N-((R)-1-amino-1-oxo-3-phenylpropan-2-yl)-5-guanidinopentanamide USP/EP/BP
  • DTP3 inhibitor
  • cancer,DTP 3,inhibit,Inhibitor,Janus kinase,DNA/RNA Synthesis,NF-κB,DTP-3,tumor,GADD45β,DTP3,JAK
CAS:
1809784-29-9
MF:
C26H35N7O5
MW:
525.6
Mol File:
1809784-29-9.mol
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(R)-2-((R)-2-acetamido-3-(4-hydroxyphenyl)propanamido)-N-((R)-1-amino-1-oxo-3-phenylpropan-2-yl)-5-guanidinopentanamide Chemical Properties

Density 
1.35±0.1 g/cm3(Predicted)
solubility 
DMSO:100.0(Max Conc. mg/mL);190.26(Max Conc. mM)
Ethanol:100.0(Max Conc. mg/mL);190.26(Max Conc. mM)
Water:100.0(Max Conc. mg/mL);190.26(Max Conc. mM)
pka
9.83±0.15(Predicted)
form 
Solid
color 
White to off-white
CAS DataBase Reference
1809784-29-9
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(R)-2-((R)-2-acetamido-3-(4-hydroxyphenyl)propanamido)-N-((R)-1-amino-1-oxo-3-phenylpropan-2-yl)-5-guanidinopentanamide Usage And Synthesis

Uses

DTP3 is a selective GADD45β/MKK7 inhibitor, which inhibits the cancer-selective NF-κB survival pathway. It specifically kills cells and induces apoptosis in MM cells without being toxic to normal cells.m

(R)-2-((R)-2-acetamido-3-(4-hydroxyphenyl)propanamido)-N-((R)-1-amino-1-oxo-3-phenylpropan-2-yl)-5-guanidinopentanamideSupplier

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(R)-2-((R)-2-acetamido-3-(4-hydroxyphenyl)propanamido)-N-((R)-1-amino-1-oxo-3-phenylpropan-2-yl)-5-guanidinopentanamide(1809784-29-9)Related Product Information