1-Benzyl-4-methyl-piperidin-3-one hydrochloride Chemical Properties

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

Appearance

White to off-white Solid

InChI

InChI=1S/C13H17NO.ClH/c1-11-7-8-14(10-13(11)15)9-12-5-3-2-4-6-12;/h2-6,11H,7-10H2,1H3;1H

InChIKey

PZBKCGGUKLHTJJ-UHFFFAOYSA-N

SMILES

C(C1C=CC=CC=1)N1CCC(C)C(=O)C1.Cl

1-Benzyl-4-methyl-piperidin-3-one hydrochloride Usage And Synthesis

Uses

1-Benzyl-4-methyl-piperidin-3-one hydrochloride was used for the preparation of key intermediates of tofacitinib. Protein IR89 was utilized to catalyze the generation of (3R, 4R)-1-benzyl-N, 4-dimethylpiperidin-3-amine dihydrochloride from 1-benzyl-4-methylpiperidin-3-one or its hydrochloride and methylamine or its hydrochloride.

1-Benzyl-4-methyl-piperidin-3-one hydrochloride(1303968-15-1)Related Product Information

• Tofacitinib Impurity 19
• Tofacitinib impurity T
• Methyl (4-Methylpiperidin-3-yl)carbaMate
• 4-CHLORO-7-TOSYL-7H-PYRROLO[2,3-D]PYRIMIDINE
• BENZYL ETHYL ETHER
• 4-chloro-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine
• N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
• Tofacitinib Impurity 85
• N-((3R,4S)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
• 4-Amino-2,6-dichloropyrimidine
• Malonyl chloride
• Benzyl chloride
• 6-AMINO-5(2,2-DIETHOXYETHYL)-4-HYDROXY-2-MERCAPTOPYRIMIDINE
• CYANOACETIC ACID-OSU
• N-Hydroxysuccinimide
• Tofacitinib Impurity 29
• N-Methyl-N-((3S,4S)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine
• (3S,4S)-Tofacitinib