ChemicalBook > Product Catalog > Chemical Reagents > Organic reagents > Aromatic ketones > 1(2H)-Phthalazinone
1(2H)-Phthalazinone
1(2H)-Phthalazinone Basic information
- Product Name:
- 1(2H)-Phthalazinone
- Synonyms:
-
- BENZO[D]PYRIDAZIN-1(2H)ONE
- 2H-Phthalazin-1-one
- 1(2H)-Phthalazinone, 98+%
- 1,2-Dihydrophthalazine-1-one
- Pthalazone
- 1,2-Dihydro-1-oxophthalazine, Benzo[d]pyridazin-1(2H)-one, Phthalazone
- 1(2H)-Phthalazinone, 98+% 5GR
- Benzo[d]pyridazin-1(2H)one 1(2H)-Phthalazinone
- CAS:
- 119-39-1
- MF:
- C8H6N2O
- MW:
- 146.15
- EINECS:
- 204-319-8
- Product Categories:
-
- Aldehyde
- Miscellaneous
- Mol File:
- 119-39-1.mol
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1(2H)-Phthalazinone Chemical Properties
- Melting point:
- 183-185 °C(lit.)
- Boiling point:
- 337°C(lit.)
- Density
- 1.2312 (rough estimate)
- refractive index
- 1.4900 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
- pka
- 12.29±0.20(Predicted)
- form
- Crystalline Powder
- color
- Off-white to pale yellow
- BRN
- 3654
- InChIKey
- IJAPPYDYQCXOEF-UHFFFAOYSA-N
- CAS DataBase Reference
- 119-39-1(CAS DataBase Reference)
- EPA Substance Registry System
- 1(2H)-Phthalazinone (119-39-1)
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Safety Information
- Hazard Codes
- Xn
- Risk Statements
- 22-68-36/37/38
- Safety Statements
- 22-24/25-36/37/39-26
- WGK Germany
- 3
- RTECS
- TH9185000
- HazardClass
- IRRITANT
- HS Code
- 29339990
- Hazardous Substances Data
- 119-39-1(Hazardous Substances Data)
- Toxicity
- mouse,LD50,intravenous,180mg/kg (180mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#00139,
MSDS
- Language:English Provider:Benzo[d]pyridazin-1(2H)one
- Language:English Provider:SigmaAldrich
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1(2H)-Phthalazinone Usage And Synthesis
Chemical Properties
Off-white to pale yellow crystalline powder
Uses
Phthalazone is a remarkable scaffold in drug discovery. Also, functions as an oxidative metabolic pathway of lenvatinib mediated by aldehyde oxidase.
Definition
ChEBI: Phthalazin-1(2H)-one is a member of phthalazines.
General Description
Pale yellow crystals. Insoluble in water.
Air & Water Reactions
Insoluble in water.
Fire Hazard
Flash point data for 1(2H)-Phthalazinone are not available. 1(2H)-Phthalazinone is probably combustible.
Purification Methods
Phthalazone crystallises from H2O or EtOH and sublimes in vacuo. [Beilstein 24 H 142, 24 24 III/IV 400.]
1(2H)-Phthalazinone Preparation Products And Raw materials
Preparation Products
Raw materials
1(2H)-PhthalazinoneSupplier
NingBo Sialon Chem Co., Ltd. Gold
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- 0574-28809768 18658497215
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J & K SCIENTIFIC LTD.
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- 010-82848833 400-666-7788
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- 021-61259108 18621169109
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INTATRADE GmbH
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- +49 3493/605464
- sales@intatrade.de
TCI (Shanghai) Development Co., Ltd.
- Tel
- 021-67121386
- Sales-CN@TCIchemicals.com
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1(2H)-Phthalazinone(119-39-1)Related Product Information
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- Nabumetone
- Metribuzin
- Toltrazuril
- 2-Acetonaphthone
- Hexazinone
- 4-Chloro-1(2H)-phthalazinone, 98%
- (4-OXO-3,4-DIHYDROPHTHALAZIN-1-YL)ACETIC ACID
- 1(2H)-PHTHALAZINONE, 4-PHENYL-
- 1,2H-PHTHALAZONE
- 4-(4-Chloro-benzyl)-2H-phthalazin-1-one
- 1(2h)-phthalazinone,4-((4-chlorophenyl)methyl)-2-(hexahydro-1-methyl-1h-azepi
- 1(2h)-phthalazinone,hydrazone,monohydrochlorid