AC-DEVD-AMC Chemical Properties

Boiling point:

1200.1±65.0 °C(Predicted)

Density 

1.423±0.06 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

DMSO: 10 mM

form 

powder

pka

4.09±0.10(Predicted)

color 

white

InChIKey

ALZSTTDFHZHSCA-RNVDEAKXSA-N

Safety Information

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

AC-DEVD-AMC Usage And Synthesis

Uses

N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-methylcoumarin has been used as a substrate for caspase-3 assay in human colon cancer cell line and in bone marrow mesenchymal stem cells.

Biochem/physiol Actions

Fluorogenic substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase.

AC-DEVD-AMC(169332-61-0)Related Product Information

• 4-Methylcumarin
• N-acetyl aspartyl-glutaMic acid
• AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN
• AC-DEVD-AFC
• AC-DEVD-CHO
• AC-DEVD-AMC
• 4-(3-METHOXY-PHENYLAMINO)-BUTAN-1-OL
• 4-(3-METHOXYANILINO)-4-OXOBUTANOIC ACID
• CHEMBRDG-BB 5539774
• CASPASE-3 SUBSTRATE AC-DEVD-AMC TFA
• SUC-ALA-ALA-ALA-AMC