Cyclopenthiazide CAS#: 742-20-1

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Cyclopenthiazide

Basic information Safety Supplier Related

Cyclopenthiazide Basic information

Product Name:

Cyclopenthiazide

Synonyms:

2h-1,2,4-benzothiadiazine-7-sulfonamide,6-chloro-3-(cyclopentylmethyl)-3,4-dih
3-cyclopentylmethylhydrochlorothiazidederiv
cyclomethiazide
navidrix
salimed
salimid
su8341
tsiklometiazid

CAS:

742-20-1

MF:

C13H18ClN3O4S2

MW:

379.88

EINECS:

212-012-5

Product Categories:

Aromatics
Heterocycles
Intermediates & Fine Chemicals
Pharmaceuticals
Sulfur & Selenium Compounds
Active Pharmaceutical Ingredients

Mol File:

742-20-1.mol

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Cyclopenthiazide Chemical Properties

Melting point:: 230°
Boiling point:: 605.6±65.0 °C(Predicted)
Density: 1.3650 (rough estimate)
refractive index: 1.6100 (estimate)
pka: 9.00±0.40(Predicted)
Water Solubility: 50mg/L(room temperature)
CAS DataBase Reference: 742-20-1(CAS DataBase Reference)
EPA Substance Registry System: 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(cyclopentylmethyl)-3,4-dihydro-, 1,1-dioxide (742-20-1)

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Safety Information

Toxicity: LD50 in rats, mice (mg/kg): 141.8 ±24, 232.4 ±25 i.v. (Barrett)

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Cyclopenthiazide Usage And Synthesis

Uses

Cyclopenthiazide is a thiazide diuretic. Cyclopenthiazide is used in the treatment of oedema caused by conditions such as kidney disease, liver cirrhosis and pre-menstrual syndrome as well as in the treatment of hypertension.

Uses

Antihypertensive;Sodium Chloride Symporter Inhibitor

World Health Organization (WHO)

Cyclopenthiazide, a thiazide diuretic, was introduced in 1968. It continues to be used mainly in combination drugs.

CyclopenthiazideSupplier

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