5-FLUORO-ALPHA-METHYLTRYPTAMINE HYDROCHLORIDE Chemical Properties

Melting point:

225-226 °C (decomp)

storage temp. 

−20°C

solubility 

DMF: 5 mg/ml; DMSO: 15 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.50 mg/ml; Ethanol: 10 mg/ml; Methanol: 1 mg/ml

form 

A crystalline solid

CAS DataBase Reference

776-56-7

5-FLUORO-ALPHA-METHYLTRYPTAMINE HYDROCHLORIDE Usage And Synthesis

Uses

5-Fluoro-α-methyltryptamine hydrochloride may cause an increase in intracellular levels of 5-HT followed by an increase in 5-HT release. 5-Fluoro-α-methyltryptamine hydrochloride exhibits EC50 values of 37 nM, 14 nM, 78 nM and 8.47 nM for DA, 5HT, NE and 5-HT2A, respectively[1][2].

References

[1] N Chairungsrilerd, et al. Effect of gamma-mangostin through the inhibition of 5-hydroxy-tryptamine2A receptors in 5-fluoro-alpha-methyltryptamine-induced head-twitch responses of mice. Br J Pharmacol. 1998 Mar;123(5):855-62. DOI:10.1038/sj.bjp.0701695
[2] Bruce E Blough, et al. Alpha-ethyltryptamines as dual dopamine-serotonin releasers. Bioorg Med Chem Lett. 2014 Oct 1;24(19):4754-4758. DOI:10.1016/j.bmcl.2014.07.062

5-FLUORO-ALPHA-METHYLTRYPTAMINE HYDROCHLORIDE(776-56-7)Related Product Information

• TRYPTAMINE HYDROCHLORIDE
• RARECHEM AN KD 1422
• RARECHEM AN KB 2239
• 5-FLUORO-ALPHA-METHYLTRYPTAMINE HYDROCHLORIDE
• RARECHEM AN KD 1785
• RARECHEM AN KD 0579
• RARECHEM AN KD 2249
• RARECHEM AN KB 1421
• RARECHEM AN KB 1781