ChemicalBook > Product Catalog > Organic Chemistry > Alcohols,Phenols,Phenol alcohols > N-Boc-PEG5-alcohol
N-Boc-PEG5-alcohol
N-Boc-PEG5-alcohol Basic information
- Product Name:
- N-Boc-PEG5-alcohol
- Synonyms:
-
- tert-Butyl (14-hydroxy-3,6,9,12-tetraoxatetradecyl)carbamate
- tert-Butyl N-2-2-2-2-(2-hydroxyethoxy)ethoxyethoxyethoxyethylcarbamate
- N-Boc-PEG5-alcohol
- N-Boc-PEG5-alcoh
- Boc-NH-PEG5-OH
- NHBoc-PEG5-OH
- 5,8,11,14-Tetraoxa-2-azahexadecanoic acid, 16-hydroxy-, 1,1-dimethylethyl ester
- t-boc-N-amido-PEG5-alcohol
- CAS:
- 1404111-67-6
- MF:
- C15H31NO7
- MW:
- 337.41
- Product Categories:
-
- peg
- Mol File:
- 1404111-67-6.mol
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N-Boc-PEG5-alcohol Chemical Properties
- Boiling point:
- 451.5±40.0 °C(Predicted)
- Density
- 1.083±0.06 g/cm3(Predicted)
- storage temp.
- Storage temp. 2-8°C
- solubility
- Soluble in DCM, Methanol
- pka
- 12.23±0.46(Predicted)
- form
- liquid
- color
- Colourless to light yellow
- InChI
- InChI=1S/C15H31NO7/c1-15(2,3)23-14(18)16-4-6-19-8-10-21-12-13-22-11-9-20-7-5-17/h17H,4-13H2,1-3H3,(H,16,18)
- InChIKey
- PBWLVPPLXJCLBC-UHFFFAOYSA-N
- SMILES
- C(OC(C)(C)C)(=O)NCCOCCOCCOCCOCCO
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N-Boc-PEG5-alcohol Usage And Synthesis
Description
N-Boc-PEG5-alcohol is a PEG linker containing a hydroxyl group and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Uses
N-Boc-PEG5-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
N-Boc-PEG5-alcoholSupplier
Guangzhou Hongyuan Chemical Co.,Ltd Gold
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- 15817493340
- 981810490@qq.com
Aikon International Limited Gold
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- 025-66113011 13155353615
- qzhang@aikonchem.com
Yaopu(Shanghai) Pharmaceutical Technology Co., Ltd Gold
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- 021-50929289 18616309303
- sales@ypptech.com.cn
Henan Mengtai Pharmaceutical Technology Co., Ltd Gold
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- 176345344 7 17634854698
- 1959525201@qq.com
PharmaBlock Sciences (Nanjing),Inc.
- Tel
- 025-86918202 4000255188
- sales@pharmablock.com
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N-Boc-PEG5-alcohol(1404111-67-6)Related Product Information
- Boc-NH-PEG(5)-COOH(22atoMs)
- t-Boc-N-amido-PEG5-acid
- O-(2-AMINOETHYL)-O'-(2-(BOC-AMINO)ETHYL)
- N-Boc-PEG4-bromide
- 1-BOC-AMINO-3,6,9-TRIOXAUNDECANYL-11-BROMIDE
- 2-(2-Methoxyethoxy)ethanamine
- Bromo-PEG3-Acid
- FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID
- Hydroxy-PEG3-t-butyl acetate
- 11-AZIDO-3 6 9-TRIOXAUNDECAN-1-AMINE
- t-Boc-N-amido-PEG2-acid
- Amino-PEG1-t-Butyl ester
- HO-PEG24-OH
- H2N-PEG2-tBu
- 5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid,1-(9-fluren-9-ylmethyl)ester
- H2N-PEG4-tBu
- 5-CHLORO-2-METHOXYBENZENESULFONYL CHLORIDE
- t-Boc-N-Amido-PEG4-propargyl