Azide-PEG4-Tos
Azide-PEG4-Tos Basic information
- Product Name:
- Azide-PEG4-Tos
- Synonyms:
-
- Azide-PEG4-Tos
- Azide-PEG5-Tos
- N3-PEG5-Tos
- Azido-PEG5-Tos
- Azido-PEG5-OTs
- N3-PEG5-TOS AZIDE-PEG5-TOS
- 14-azido-3,6,9,12-tetraoxatetradecyl 4-methylbenzenesulfonate
- N3-PEG5-Tos/Ethanol, 2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]-, 1-(4-methylbenzenesulfonate)
- CAS:
- 236754-49-7
- MF:
- C17H27N3O7S
- MW:
- 417.48
- Product Categories:
-
- peg
- Mol File:
- 236754-49-7.mol
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Azide-PEG4-Tos Chemical Properties
- storage temp.
- Storage temp. 2-8°C
- form
- Liquid
- color
- Colorless to light yellow
- InChI
- InChI=1S/C17H27N3O7S/c1-16-2-4-17(5-3-16)28(21,22)27-15-14-26-13-12-25-11-10-24-9-8-23-7-6-19-20-18/h2-5H,6-15H2,1H3
- InChIKey
- RCRFPWKHJGMATE-UHFFFAOYSA-N
- SMILES
- S(C1C=CC(C)=CC=1)(=O)(=O)OCCOCCOCCOCCOCCN=[N+]=[N-]
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Azide-PEG4-Tos Usage And Synthesis
Description
Azide-PEG5-Tos is a crosslinking reagent with two functional groups. PEG spacer increases solubility in aqueous media. The azide(N3) group is reactive with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The tosyl group is a good leaving group for nucleophilic substitution reactions.
Biological Activity
Azide-PEG5-Tos (Azido-PEG5-OTs) is a cleavable 5-unit PEG ADC linker for the synthesis of antibody-drug conjugates (ADCs).
in vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
target
| Cleavable
|
Azide-PEG4-TosSupplier
Affinity（Wuhan）Ltd. Gold
- Tel
- 15841022315
- sales@affinitytech.cn
Xi'an Kaixin Biotechnology Co., Ltd Gold
- Tel
- 029-68881181 13619217766
- 3495811982@qq.com
Hunan HuaTeng Pharmaceutical Co., Ltd.,
- Tel
- 400-8592883
- sales@huatengsci.com
Mashilabs (Shanghai) Co.,Ltd.
- Tel
- 19916721580
- mafarm@126.com
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
- Tel
- 0431-0431-80514535 19917294565
- et@chemextension.com
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