Hydroxy-PEG2-CH2CO2t-Bu Chemical Properties

Boiling point:

306.1±22.0 °C(Predicted)

Density 

1.062±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

Soluble in Water, DMSO, DCM, DMF

pka

14.35±0.10(Predicted)

form 

liquid

color 

Colourless

Safety Information

HS Code 

2942000090

Hydroxy-PEG2-CH2CO2t-Bu Usage And Synthesis

Description

Hydroxy-PEG2-CH2CO2tBu is a PEG linker containing a hydroxyl group with a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

Hydroxy-PEG2-CH2CO2tBu was a useful reagent in the study for potentiator-corrector agonist of cystic fibrosis mutant protein ΔF508-CFTR preparation.

Hydroxy-PEG2-CH2CO2t-Bu(149299-82-1)Related Product Information

• H2N-PEG2-CH2COOtBu
• tert-butyl 2-(2-(2-(4-hydroxybutoxy)ethoxy)ethoxy)acetate
• PEG4-tert-butyl acetate
• Hydroxy-PEG3-t-butyl acetate
• Hydroxy-PEG1-CH2CO2tBu
• Hydroxy-PEG6-CH2CO2tBu