m-PEG3-Tos
m-PEG3-Tos Basic information
- Product Name:
- m-PEG3-Tos
- Synonyms:
-
- MeO(CH2)2O(CH2)2OTs
- m-PEG3-Tos
- Ethanol, 2-(2-methoxyethoxy)-, 4-methylbenzenesulfonate
- MPEG3-TOSYLATE
- m-PEG2-Tos
- Ethanol, 2-(2-methoxyethoxy)-, 1-(4-methylbenzenesulfonate)
- mPEG2-Tosylate
- m-dPEG??-tosylate
- CAS:
- 50586-80-6
- MF:
- C12H18O5S
- MW:
- 274.33
- Mol File:
- 50586-80-6.mol
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m-PEG3-Tos Chemical Properties
- Boiling point:
- 392.3±27.0 °C(Predicted)
- Density
- 1.179±0.06 g/cm3(Predicted)
- form
- Solid-Liquid Mixture
- color
- Colorless to white
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m-PEG3-Tos Usage And Synthesis
Description
m-PEG3-Tos is a PEG linker containing a tosyl group. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
Biological Activity
m-PEG2-Tos is a non-cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs). It can also be used as a PROTAC linker for PROTAC synthesis. .
in vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
target
| Non-cleavable < span> | PEGs
|
m-PEG3-TosSupplier
T&W GROUP
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- 021-61551611 13296011611
- contact@trustwe.com
Nanjing Anyan Pharmaceutical Technology Co. , Ltd.
- Tel
- 025-58361178 17351780683
- amy.xiang@ally-chem.com
Shanghai Raise Chemical Technology Co.,Ltd
- Tel
- 15026594951
- rs@raise-chem.com
Jinan elephant international trading co., LTD
- Tel
- 13006575422@163.com
Beijing Jin Ming Biotechnology Co., Ltd.
- Tel
- 010-60605840 18892239720
- psaitong@jm-bio.com
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m-PEG3-Tos(50586-80-6)Related Product Information
- m-PEG3-Mal
- m-PEG3-Sulfone-PEG3-azide
- Diethylene Glycol 2-Bromoethyl Methyl Ether
- m-PEG3-Sulfone-PEG3-acid
- m-PEG3-NHS ester
- m-PEG3-Sulfone-PEG4-propargyl
- m-PEG3-aldehyde
- m-PEG3-Sulfone-PEG2-OH
- 2-[2-(2-methoxyethoxy)ethoxy]-ethanethiol
- 2-[2-(2-METHOXYETHOXY)ETHOXY]ACETIC ACID
- m-PEG3-Sulfone-PEG3-t-butyl ester