N-Pyridin-2-yl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzamide Chemical Properties

Boiling point:

414.1±25.0 °C(Predicted)

Density 

1.16±0.1 g/cm3(Predicted)

storage temp. 

2-8°C

pka

12.08±0.70(Predicted)

Appearance

White to off-white Solid

InChI

InChI=1S/C18H21BN2O3/c1-17(2)18(3,4)24-19(23-17)14-10-8-13(9-11-14)16(22)21-15-7-5-6-12-20-15/h5-12H,1-4H3,(H,20,21,22)

InChIKey

BFQWQKOPPQDARN-UHFFFAOYSA-N

SMILES

C(NC1=NC=CC=C1)(=O)C1=CC=C(B2OC(C)(C)C(C)(C)O2)C=C1

CAS DataBase Reference

1383385-64-5

N-Pyridin-2-yl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzamide Usage And Synthesis

Application

N-(pyridin-2-yl)-4-(4,4,5,5-tetramethylL-1,3,2-dioxoboron-2-yl)carboxamide is an organic synthesis intermediate and pharmaceutical intermediate used in organic synthesis and pharmaceutical research and development.

Chemical Properties

Pale yellow to Off-white powder

Definition

N-Pyridin-2-yl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzamide is a second generation BTK inhibitor Acalabrutinib intermediate.

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