Febuxostat Descyano Impurity Chemical Properties

Melting point:

192-194°C

Boiling point:

471.5±55.0 °C(Predicted)

Density 

1.213±0.06 g/cm3(Predicted)

storage temp. 

Hygroscopic, -20°C Freezer, Under inert atmosphere

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

1.30±0.37(Predicted)

form 

Solid

color 

Off-White to Pale Beige

Stability:

Hygroscopic

Febuxostat Descyano Impurity Usage And Synthesis

Uses

3-Descyano Febuxostat is an impurity of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.

Febuxostat Descyano Impurity(1206550-99-3)Related Product Information

• Febuxostat
• 2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5-carboxylic acid
• 2-(4-HYDROXY-PHENYL)-4-METHYL-THIAZOLE-5-CARBOXYLIC ACID
• ethyl 2-(4-butoxy-3-formylphenyl)-4-methylthiazole-5- carboxylate
• FeBuxostat Impurity 32
• 2-(4-(sec-butoxy)-3-cyanophenyl)-4-methylthiazole-5-carboxylic acid
• Febuxostat Bromo Impurity
• Febuxostat Impurity 14
• 2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid
• 2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-Methyl-5-thiazolecarboxylic Acid
• ethyl 2-(4-butoxy-3-cyanophenyl)-4-methylthiazole-5- carboxylate
• FeBuxostat Impurity 18
• ethyl 2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5- carboxylate
• 2-(3-cyano-4-propoxyphenyl)-4-methylthiazole-5-carboxylic acid
• Febuxostat impurity 37
• FeBuxostat Impurity 33
• FeBuxostat Impurity 26
• Febuxostat Acyl-β-D-glucuronide