Basic information Safety Supplier Related

Pentaethylene glycol mono methyl ether tosylate

Basic information Safety Supplier Related

Pentaethylene glycol mono methyl ether tosylate Basic information

Product Name:
Pentaethylene glycol mono methyl ether tosylate
Synonyms:
  • TsO(CH2CH2O)5Me
  • Pentaethylene glycol mono methyl ether tosylate
  • m-PEG6-OTs
  • m-PEG6-Tos
  • 2,5,8,11,14-Pentaoxahexadecan-16-ol, 4-methylbenzenesulfonate
  • 2,5,8,11,14-pentaoxahexadecan-16-yl 4-methylbenzenesulfonate
  • 2,5,8,11,14-pentaoxahexadecan-16-yl 4-methylbenzenesulfonate(WXC06914)
  • 3,6,9,12,15-Pentaoxahexadecan-1-ol, 1-(4-methylbenzenesulfonate)
CAS:
80755-67-5
MF:
C18H30O8S
MW:
406.49
Mol File:
80755-67-5.mol
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Pentaethylene glycol mono methyl ether tosylate Chemical Properties

Boiling point:
502.7±50.0 °C(Predicted)
Density 
1.158±0.06 g/cm3(Predicted)
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Pentaethylene glycol mono methyl ether tosylate Usage And Synthesis

Description

m-PEG6-Tos is a PEG linker containing a tosyl group. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

m-PEG5-Tos is a derivative of silybin ethers, extracted from patent CN105037337A (compound III-c). m-PEG5-Tos is a PEG-based PROTAC linker can be used in the synthesis of Silymarin (HY-W043277)[1].

IC 50

PEGs

References

[1] Yuxia Zhao, et al. Derivative of silybin ethers, and synthetic method and application thereof. Patent CN105037337A.

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