Basic information Safety Supplier Related

SU 5205

Basic information Safety Supplier Related

SU 5205 Basic information

Product Name:
SU 5205
Synonyms:
  • SU 5205
  • 2H-Indol-2-one, 3-[(4-fluorophenyl)methylene]-1,3-dihydro-
  • SU 5205; SU-5205; SU5205
  • mitogenesis,Inhibitor,VEGFR2,Vascular endothelial growth factor receptor,FLK-1,SU-5205,endothelial,VEGFR,SU5205,inhibit
CAS:
3476-86-6
MF:
C15H10FNO
MW:
239.24
Mol File:
3476-86-6.mol
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SU 5205 Chemical Properties

Melting point:
194-196 °C
Boiling point:
435.3±45.0 °C(Predicted)
Density 
1.306±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMF: 50 mg/ml; DMSO: 50 mg/ml; DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml; Ethanol: 5 mg/ml
form 
A crystalline solid
pka
12.69±0.20(Predicted)
color 
White to yellow
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SU 5205 Usage And Synthesis

Biological Activity

SU5205 is an inhibitor of VEGF receptor 2 (VEGFR2/FLK-1) with IC50 of 9.6 μM.

in vitro

SU5205 inhibits ligand-induced endothelial mitogenesis for VEGF with an IC 50 of 5.1 μM.

target

TargetValue
VEGFR2
(Cell-free assay)
9.6 μM

SU 5205Supplier

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Email
cfzhang@aikonchem.com
Shanghai JiYi Biotechnology Co. Ltd.
Tel
13621943973
Email
sales@shjiyipharmatech.com
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Email
3008007409@qq.com
Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Email
klq@cw-bio.com
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ:65489617 15618227136
Email
Sales@ATKchemical.com