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Bosutinib Impurity 5

Basic information Safety Supplier Related

Bosutinib Impurity 5 Basic information

Product Name:
Bosutinib Impurity 5
Synonyms:
  • Bosutinib isomer 1
  • 3-Quinolinecarbonitrile, 4-[(3,5-dichloro-4-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-
  • Bosutinib Isomer I (PF-06651481-00)
  • Bosutinib Isomer I
CAS:
1391063-17-4
MF:
C26H29Cl2N5O3
MW:
530.45
Mol File:
1391063-17-4.mol
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Bosutinib Impurity 5 Chemical Properties

solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
form 
Solid
color 
White to Light Brown
Stability:
Stable under recommended storage conditions., Stable Under Recommended Storage C
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Bosutinib Impurity 5 Usage And Synthesis

Uses

Kinase inhibitors, such as?bosutinib,?are useful cancer drugs but their target specificity is not fully understood. 4-[(3,5-Dichloro-4-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile has been employed as a clinical kinase inhibitor bosutinib to elucidate the recognition mechanism between the ATP-binding site and the compound.

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