Dimethylcopperlithium Chemical Properties

solubility 

sol THF, Et2O

Dimethylcopperlithium Usage And Synthesis

Uses

Dimethylcopperlithium is used as a methylating reagent; undergoes conjugate addition reactions, 1,2-addition reactions, substitution reactions with alkyl, vinyl, and allyl substrates, carbocupration of alkynes, and reduction of carbon-heteroatom bonds.

Preparation

Dimethylcopperlithium free of LiI can be prepared from isolated Methylcopper, and the reagent can also be prepared in the presence of complexing agents from CuI.SBu2, Copper(I) Iodide-Tributylphosphine, or CuBr.SMe2. Polymer-supported Me2CuLi is also available.

storage

Dimethylcopperlithium is air- and moisture-sensitive; handle under inert atmosphere in a fume hood.

Dimethylcopperlithium(15681-48-8)Related Product Information

• ISOPROPYLLITHIUM
• N-HEXYLLITHIUM
• Methyllithium
• Ethyllithium
• Phenyllithium
• ISOBUTYLLITHIUM
• tert-Butyllithium
• N-PROPYLLITHIUM
• SEC-BUTYLLITHIUM
• MAGNESIUM DIETHYL
• Diethylzinc
• Dimethyl magnesium
• Lithium diisopropylamide
• DIMETHYLZINC
• DI-N-BUTYL ZINC
• DIISOPROPYL ZINC 1.0M SOLUTION IN TOLU&
• LITHIUM DICYCLOHEXYLAMIDE
• dioctylmagnesium