Epilancin 15X Usage And Synthesis

Biological Activity

Epilancin 15X is a lantibiotic that has an antimicrobial activity in the nanomolar concentration range towards Staphylococcus simulans.

Synthesis

The recently discovered lantibiotic epilancin 15X produced by Staphylococcus epidermidis 15X154 is active against several pathogenic bacteria, including methicillin‐resistant S. aureus and vancomycin‐resistant Enterococci. Epilancin 15X contains an unusual N‐terminal lactate group (Lac) that could be important for its bioactivity.