m-PEG17-acid Chemical Properties

Boiling point:

763.8±60.0 °C(Predicted)

Density 

1.114±0.06 g/cm3(Predicted)

pka

4.28±0.10(Predicted)

m-PEG17-acid Usage And Synthesis

Biological Activity

m-PEG17-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

m-PEG17-acid(2346581-96-0)Related Product Information

• INDEX NAME NOT YET ASSIGNED
• 4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64,67,70-Tricosaoxahenheptacontanoic acid
• mPEG22-NH2
• Methyl-PEG24-Amine
• m-PEG11-acid
• mPEG17-NH2