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ETANIDAZOLE

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ETANIDAZOLE Basic information

Product Name:
ETANIDAZOLE
Synonyms:
  • N-[2-HYDROXYETHYL]-2-NITRO-1H-IMIDAZOLE-1-ACETAMIDE
  • ETANIDAZOLE
  • n-(2-hydroxyethyl)-1-(2-nitro-1-imidazolyl)acetamide
  • n-(2-hydroxyethyl)-2-nitro-1h-imidazole-1-acetamid
  • n-(2-hydroxyethyl)-2-nitro-imidazole-1-acetamid
  • nsc301467
  • Radinyl
  • SP-2508
CAS:
22668-01-5
MF:
C7H10N4O4
MW:
214.18
Mol File:
22668-01-5.mol
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ETANIDAZOLE Chemical Properties

Melting point:
162-163° (Beaman); mp 164.5-165° (Lee)
Boiling point:
354.3°C (rough estimate)
Density 
1.4480 (rough estimate)
refractive index 
1.6700 (estimate)
storage temp. 
2-8°C
solubility 
Acetone (Slightly), Methanol (Slightly)
form 
Solid
pka
13.74±0.46(Predicted)
color 
White to Off-White
Stability:
Hygroscopic
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
NI3355000

MSDS

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ETANIDAZOLE Usage And Synthesis

Uses

Antineoplastic (hypoxic cell radiosensitizer).

Uses

Etanidazole is a kind of hypoxic radiosensitizer (a drug that sensitizes tumour cells to radiation therapy). Etanidazole is used in conjunction with Paclitaxel (P132500) to treat glioma, and is also used with Carboplatin (C177500) to treat advanced ovarian cancer.

Definition

ChEBI: A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2-nitro-1H-imidazol-1-yl)acetic acid with the amino group of ethanolamine. Used as a radiosensitising agent for hypoxic tumour cells.

brand name

Radinyl (Roberts Pharmaceutical).

ETANIDAZOLESupplier

Tongchuang Pharma(Suzhou). Co., Ltd. Gold
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0512-63263366 18912765016
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tongtf110@sina.com
J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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jkinfo@jkchemical.com
LGM Pharma
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1-(800)-881-8210
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Hangzhou J&H Chemical Co., Ltd.
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0571-+86-571-87396432
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sales@jhechem.com
Shanghai HuanChuan Industry Co.,Ltd.
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021-61478794
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sales@hcshhai.com