Basic information Safety Supplier Related

5-Amino-1-(4-trifluoromethylphenyl)-1H-pyrazole-4-carbonitrile

Basic information Safety Supplier Related

5-Amino-1-(4-trifluoromethylphenyl)-1H-pyrazole-4-carbonitrile Basic information

Product Name:
5-Amino-1-(4-trifluoromethylphenyl)-1H-pyrazole-4-carbonitrile
Synonyms:
  • 5-Amino-1-(4-trifluoromethylphenyl)-1H-pyrazole-4-carbonitrile
  • 1H-Pyrazole-4-carbonitrile, 5-amino-1-[4-(trifluoromethyl)phenyl]-
  • 5 amino 1 [4 (trifluoromethyl)phenyl] 1H pyrazole 4 carbonitrile,5amino1[4(trifluoromethyl)phenyl]1Hpyrazole4carbonitrile
  • Xanthine oxidase-IN-14
  • Xanthine dehydrogenase Inhibitor 1
  • 5-amino-1-[4-(trifluoromethyl)phenyl]-1H-pyrazole-4-carbonitrile, 10 mM in DMSO
CAS:
80025-67-8
MF:
C11H7F3N4
MW:
252.2
Mol File:
80025-67-8.mol
More
Less

5-Amino-1-(4-trifluoromethylphenyl)-1H-pyrazole-4-carbonitrile Usage And Synthesis

Uses

Xanthine oxidase-IN-14 (Compound 3f) is an inhibitor for xanthine oxidase, with IC50 >100 μM. Xanthine oxidase-IN-14 inhibits proliferations of cancer cells MCF-7, NCI-H460 and SF-268, with IC50 greater than 150 μM[1].

References

[1] Gupta S, et al., Synthesis of N-aryl-5-amino-4-cyanopyrazole derivatives as potent xanthine oxidase inhibitors. Eur J Med Chem. 2008 Apr;43(4):771-80. DOI:10.1016/j.ejmech.2007.06.002

5-Amino-1-(4-trifluoromethylphenyl)-1H-pyrazole-4-carbonitrileSupplier

Shanghai Chaolan Chemical Technology Center
Tel
021-QQ：65489617 15618227136
Email
Sales@ATKchemical.com
Yantai ShengKailun Chemical Technology Co., Ltd.
Tel
13356901049
Email
3119594100@qq.com
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
More
Less

5-Amino-1-(4-trifluoromethylphenyl)-1H-pyrazole-4-carbonitrile(80025-67-8)Related Product Information