GSK-1440115
GSK-1440115 Basic information
- Product Name:
- GSK-1440115
- Synonyms:
-
- GSK-1440115
- [1,1'-Biphenyl]-4-carboxylic acid, 4'-[(1R)-1-[[2-(6,7-dichloro-2,3-dihydro-3-oxo-4H-1,4-benzoxazin-4-yl)acetyl]methylamino]-2-(4-morpholinyl)ethyl]-
- CAS:
- 1003878-16-7
- MF:
- C30H29Cl2N3O6
- MW:
- 598.47
- Mol File:
- 1003878-16-7.mol
More
Less
GSK-1440115 Usage And Synthesis
Uses
GSK-1440115 is an antagonist of the Urotensin II Receptor with an IC50 value of 82.3 nM[1].
References
[1] Tae-Ho Kim, et al. A Novel Urotensin II Receptor Antagonist, KR-36996 Inhibits Smooth Muscle Proliferation through ERK/ROS Pathway. Biomol Ther (Seoul). 2017 May 1;25(3):308-314. DOI:10.4062/biomolther.2016.219