ChemicalBook > Product Catalog > Analytical Chemistry > Standard > Pharmaceutical Impurity Reference Standards > (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Basic information
- Product Name:
- (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
- Synonyms:
-
- Intedanib Impurity D
- Nintedanib Impurity 34
- Nintedanib-011
- Nintedanib impurity 10/(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
- (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)meth...
- 1H-Indole-6-carboxylic acid, 2,3-dihydro-3-[[[4-(methylamino)phenyl]amino]phenylmethylene]-2-oxo-, methyl ester, (3Z)-
- Nintedanib Impurity q
- (3Z)?-2,?3-Dihydro-?3-?[[[4-?(methylamino)?phenyl]?amino]?phenylmethylene]?-?2-?oxo-?1H-?Indole-?6-?carboxylic Acid Methyl Ester
- CAS:
- 1987887-92-2
- MF:
- C24H21N3O3
- MW:
- 399.44
- Mol File:
- 1987887-92-2.mol
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(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Chemical Properties
- Melting point:
- 273 - 276°C
- Boiling point:
- 641.3±55.0 °C(Predicted)
- Density
- 1.316±0.06 g/cm3(Predicted)
- storage temp.
- Refrigerator, under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 11.16±0.20(Predicted)
- form
- Solid
- color
- Yellow to Orange
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(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Usage And Synthesis
Uses
(3Z)?-2,?3-Dihydro-?3-?[[[4-?(methylamino)?phenyl]?amino]?phenylmethylene]?-?2-?oxo-?1H-?Indole-?6-?carboxylic Acid Methyl Ester is an impurity of Nintedanib (N478290), an angiokinase inhibitor and is used in the treatment of idiopathic pulmonary fibrosis. Also inhibits the process blood vessel formation which may be used to assist in cancer therapy.
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(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate(1987887-92-2)Related Product Information
- (3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester
- 1-(2-chloroacetyl)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester
- Nintedanib
- Methyl oxindole-5-carboxylate
- N-(4-aMinophenyl)-2-chloro-N-MethylacetaMide
- 2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID
- 2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE
- N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide
- 2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID ETHYL ESTER
- Methyl 1-acetyl-2-oxoindoline-6-carboxylate
- 1-Chloro-4-(trimethoxymethyl)benzene
- METHYL OXINDOLE-7-CARBOXYLATE
- P-ANISALDEHYDE DIMETHYL ACETAL
- 1,3-DiMethyl 2-[4-(Methoxycarbonyl)-2-nitrophenyl]propanedioate
- BIBF 1202
- N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide
- N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide
- Methyl 4-chloro-3-nitrobenzoate